[Clinical use for anti-mullerian hormone in gynecology].
نویسندگان
چکیده
Anti-mullerian hormone (AMH) is a glycoprotein produced by granulosa cells of primary, pre-antral and small antral ovarian follicles and its clinical applicability has been recently demonstrated by several studies. Prediction of the response to ovarian stimulation for in vitro fertilization corresponds to the most frequent utilization of AMH in clinical practice, being routinely assessed in many services to identify subgroups of women susceptible to a poor response or to Ovarian Hyperstimulation Syndrome. There are great perspectives that AMH may be applicable to the individual determination of risk for iatrogenic gonadal injury in women with neoplasms who will be submitted to chemotherapy. It is also probable that AMH assessment will be included in protocols for the investigation of amenorrhea and oligomenorrhea, since AMH levels are increased in Polycystic Ovary Syndrome, reduced in premature ovarian failure and normal in other conditions such as hyperprolactinemia and hypogonadotropic hypogonadism. It is possible that AMH will be utilized in the future for the prediction of age at menopause and of reproductive prognosis, providing solid bases for pre-conceptive and contraceptive counseling.
منابع مشابه
P-85: Effect of Metformin on Anti-Mullerian Hormone (AMH) Level in Women with Infertility and Polycystic Ovary Syndrome
Background Women with PCOS have increased AMH levels due to accumulated preantral and small antral in follicles. Ovulation improvement following decrease in levels of AMH could accure in these patients. The purpose of this study was to evaluate the effect of metformin on anti-Mullerian hormone levels in women with polycystic ovary syndrome and infertility MaterialsAndMethods This randomized cli...
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Background The impact of cancer therapy on the reproductive potential of patients is increasingly recognized because survival rates of patients have clearly improved in recent years. The study stressed the use of AMH may allow better prediction of chemotherapy-related risk to further fertility. MaterialsAndMethods A narrative review was performed within articles published at PubMed, Elsevier, S...
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ورودعنوان ژورنال:
- Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia
دوره 35 3 شماره
صفحات -
تاریخ انتشار 2013